6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINE

Product Name
6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINE
CAS No.
1140-81-4
Chemical Name
6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINE
Synonyms
6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINE;6-Acetamido-2-methyl-4-hydroxyquinoline;N-Acetyl-4-hydroxy-2-methyl-6-quinolinamine;N-(4-Hydroxy-2-methyl-6-quinolinyl)acetamide;N-(2-methyl-4-oxo-1H-quinolin-6-yl)acetamide;N-(4-hydroxy-2-Methylquinolin-6-yl)acetaMide;Acetamide, N-(4-hydroxy-2-methyl-6-quinolinyl)-;n-(2-Methyl-4-oxo-1,4-dihydroquinolin-6-yl)acetamide
CBNumber
CB41091481
Molecular Formula
C12H12N2O2
Formula Weight
216.24
MOL File
1140-81-4.mol
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6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINE Property

Melting point:
>300 °C
Boiling point:
496.0±40.0 °C(Predicted)
Density 
1.314±0.06 g/cm3(Predicted)
solubility 
Ethyl Acetate; Toluene
pka
4.29±0.40(Predicted)
form 
Solid
color 
Yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T323233
Product name
N-(4-HYDROXY-2-METHYL-6-QUINOLINYL)ACETAMIDE
Purity
AldrichCPR
Packaging
5MG
Price
$70.9
Updated
2024/03/01
TRC
Product number
H114085
Product name
N-(4-Hydroxy-2-methyl-6-quinolinyl)acetamide
Packaging
1g
Price
$430
Updated
2021/12/16
AK Scientific
Product number
9559AJ
Product name
6-Acetamido-4-hydroxy-2-methylquinoline
Packaging
250mg
Price
$552
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA152500
Product name
6-Acetamido-2-methyl-4-hydroxyquinoline
Packaging
500mg
Price
$645
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA152500
Product name
6-Acetamido-2-methyl-4-hydroxyquinoline
Packaging
50mg
Price
$107
Updated
2021/12/16
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6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINE Chemical Properties,Usage,Production

Uses

N-(4-Hydroxy-2-methyl-6-quinolinyl)acetamide is an intermediate in the synthesis of NSC 23766 (N900280), which is a highly soluble and membrane permeable Rac GTPase inhibitor. NSC 23766 inhibits Rac GTPase by targeting Rac activation by guanine nucleotide exchange factor (GEF). NSC 23766 has been shown to inhibit the anchorage-independent growth and invasion phenotypes of human prostate cancer PC-3 cells.

Synthesis Reference(s)

Journal of the American Chemical Society, 70, p. 4065, 1948 DOI: 10.1021/ja01192a031

6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINE Suppliers

China 10 India 1 Sweden 1 United Kingdom 1 United States 2 Global 15

1140-81-4, 6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINERelated Search:

4-HYDROXY-2-METHYLQUINOLINE 4-Hydroxy-2-methylquinoline 4-Quinolinol,6-amino-(9CI) 6-AMINO-2-METHYLQUINOLINE 6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINE

  • N-(2-methyl-4-oxo-1H-quinolin-6-yl)acetamide
  • 6-Acetamido-2-methyl-4-hydroxyquinoline
  • 6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINE
  • N-(4-Hydroxy-2-methyl-6-quinolinyl)acetamide
  • N-Acetyl-4-hydroxy-2-methyl-6-quinolinamine
  • N-(4-hydroxy-2-Methylquinolin-6-yl)acetaMide
  • Acetamide, N-(4-hydroxy-2-methyl-6-quinolinyl)-
  • n-(2-Methyl-4-oxo-1,4-dihydroquinolin-6-yl)acetamide
  • 1140-81-4